Acomplia - the drug to forget about overweight
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What is Acomplia?
Acomplia (rimonabant) makes part of a new drug class called cannabinoid-1 receptor blockers (CB1), which are used to suppress appetite and make the patient consume less food. Acomplia is prescribed for treating overweight, obesity and related health risks such as diabetes or high blood pressure.
Acomplia mechanism of action
Acomplia's active ingredient acts by restricting CB1 receptors located in the brain and in other organs involved in glucose and lipid metabolism, such as adipose tissue, liver, gastrointestinal tract and muscles. When Acomplia is used it turns off the same receptors that make people hungry when smoking cannabis. The drug blocks CB1 receptors that have been recently found to make up a whole system, called endocannabinoid system (EC system), which when overactive results in an increased energy (food) intake. The EC system is a newly discovered physiological system that was observed to be strongly involved in controlling the energy balance and body weight, as well as metabolism of certain important substances.
Acomplia uses
Acomplia is used in conjunction with diet and exercise programs for the treatment of obesity and overweight in patients who also suffer from related health issues such as diabetes or increased fat levels in blood. Sanofi, manufacturer of Acomplia, also states that the drug is able to prevent the risk of cardiovascular disease. Those patients who have a large waist circumference will strongly benefit from taking Acomplia because it helps reduce several inches during a normal course.
Acomplia and smoking cessation
During the clinical studies of Acomplia, researchers have observed the highly positive effect of Acomplia over smoking patients, especially those who were striving to kick the habit. These individuals noted that it was much easier to stop smoking when on Acomplia. This is due to the fact that Acomplia affecting the CB1 receptors not only controls the appetite but is also able to affect nicotine dependency. However, the drug was not approved as a smoking cessation medication by the authorities and this benefit remains more of a side-effect rather than its target use.
Acomplia side-effects
During the clinical studies the most common of side-effects of Acomplia for treating overweight and obesity were nausea and vomiting. These symptoms have forced about 19 percent of participants to give up the studies, because of increased discomfort.
Disclaimer
The drug information presented on this site is for information purpose only, it doesn't provide the whole spectrum of this drug's use, reactions, method of action or precautions. This information has a general character and should not be used for making serious decisions. It doesn't contain any concrete instructions for any individuals. We disclaim all responsibility concerning the accuracy and reliability of this data, and/or any consequences that may arise from using and interpreting this information, as well as the damage or adverse effects to persons or property. There is no warranty, both expressed or implied, made in regards to this information.
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